File:Glutamate synaptic plasticity.jpg

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Memory formation involves 2 types of glutamate receptors: the N-methyl-D-aspartate receptor(NMDAR) and the alpha amino 3 hydroxy 5 methyl 4 isoxazole propionic acid receptor (AMPAR). These receptors sit on the surface of the postsynaptic neurons. AMPARs allow sodium to flow into the postsynaptic cell, resulting in depolarisation. NMDARs are permeable to both ionic sodium and calcium. The resulting influx of ionic calcium into the postsynaptic terminals through the NMDAR upregulates AMPARS to the membrane and increases their sensitivity to glutamate. [picture courtesy:Brain and Behavior Discovery Institute, Medical College of Georgia, Augusta]

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current14:13, 28 September 2010Thumbnail for version as of 14:13, 28 September 2010403 × 529 (57 KB)Admin (Talk | contribs) (Memory formation involves 2 types of glutamate receptors: the N-methyl-D-aspartate receptor(NMDAR) and the alpha amino 3 hydroxy 5 methyl 4 isoxazole propionic acid receptor (AMPAR). These receptors sit on the surface of the postsynaptic neurons. AMPARs a)

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