Cannabidiol significantly reduces seizures in Lennox-Gastaut syndrome


In a new study published in The New England Journal of Medicine the researchers, comparing two doses of Cannabidiol (CBD) to a placebo, reported a 41.9 percent reduction in "drop seizures" in patients taking a 20 mg/kg/d Cannabidiol (CBD) regimen, a 37.2 percent reduction in those on a 10 mg/kg/d Cannabidiol (CBD) regimen, and a 17.2 percent reduction in a group given a placebo. The phase III trial was led by principal investigator and study first co-author Orrin Devinsky, MD, a professor of neurology, neurosurgery, and psychiatry at NYU School of Medicine and director of NYU Langone's Comprehensive Epilepsy Center. The study...
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ICNA Executive Board Elections 2018


Voting for the ICNA Secretary and Treasurer positions and to the Executive Board was held from 03 April 2018 to 03 May 2018 2400 GMT. All eligible ICNA members were provided with a security code following validation of which, they were able to cast their votes on an online ballot. All active members of the ICNA were eligible to vote in this election. Associate and Junior(trainee) members were not eligible to vote according to the ICNA constitution and bye laws. Memb...
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Natalio Fejerman [1933-2018]


Natalio Fejerman, leading Argentine child neurologist and epileptologist, died on Thursday, March 29, after a short sickbed. He was 84 years old.  Natalio Fejerman was born in Buenos Aires on November 8 th , 1933. He earned his medical degree from Medical School in Buenos Aires in 1957 and started his professional training at the Children's Hospital Ricardo Gutierrez in Buenos Aires and later at Boston Children's Hospital under Prof. Cesare Lombroso. He was the head of the Department of Neu...
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Autophagy and Cell Death - Precise Mechanisms revealed

In a study published in Current Biology today, researchers from  King's College London uncovers the precise mechanisms by which autophagy leads to cell death. The  study used a  mouse model for the polyglutamine disease dentatorubral-pallidoluysian atrophy (DRPLA), progressive acquirement of an ataxic phenotype linked to severe cerebellar cellular pathology, characterized by nuclear degeneration through nucleophagy-based LaminB1 degradation and excretion.  DRPLA is caused by ...
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Hibernating ground squirrels provide clues for neuroprotection in ischemic stroke

  In a study published in The FASEB Journal a team of NIH-funded scientists reports on a potential drug that could be protective in ischemic stroke patients.  The clue for the study came from observations in hibernating ground squirrels. In these animals there is a dramatic reduction of cerebral blood flow during hibernation, yet they emerge from their sleep without any ill effects at all.  The researchers observed that a cellular process called SUMOylation goes into overdrive in ...
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