ICNC2018 Abstracts & Symposia Proposals, ICNC 2014

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Influence of congenital hypothyroidism on psychomotor performance in infants
Michelle Prado Cabral do Ouro, Maura Mikie Fukujima Goto, Maria Cecilia Marconi Pinheiro Lima, Môyra Romero Patresi, Vivian Dutra, Sofia Helena Valente Lemos-Marini, Denise Castilho Cabrera Santos, Maria Francisca Colella-Santos

Last modified: 2014-04-03

Abstract


Congenital hypothyroidism (CH) is caused by a thyroid hormone deficiency, which is present at birth, resulting in a reduction in metabolic processes that influence the development of the central nervous system. The aim of the present study was to analyze psychomotor performance in infants with CH in follow up at a neonatal reference center (NSRC) in Brazil Methods: An observational, case-control, cross-sectional study was carried out involving 48 infants with CH (mean age: 10 ± 0.7 months) and 37 without CH (mean age: 11 ± 0.7 months). The Bayley Scales of Infant and Toddler Development III were used for the evaluation, which classify motor performance as competent (low risk for delayed development), emergent risk or at risk. The chi-square test was used to compare performance categories between groups, with the level of significance set to 5% (p < 0.05). Results: No significant differences were found between groups regarding psychomotor performance on the cognitive, expressive language, fine motor skill or gross motor skill scales (p > 0.05), whereas a significant difference was found regarding receptive language (p = 0.019). Based on the present findings, children with CH are at greater risk of delayed development in receptive language skills. Moreover, the occurrence of a performance at risk only in the CH group suggests that screening should be used for developmental problems, as well as routine follow up allows early detection and intervention.


Keywords


Congenital Hypothyroidism, Child Development, Psychomotor Performance

References


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