ICNC2018 Abstracts & Symposia Proposals, ICNC 2014

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RESPIRATORY MUSCLE TRAINING IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY: clinical trial with one group
TEREZA CRISTINA CARBONARI DE FARIA, Larissa Perossi Nascimento, Samara de Oliveira Silva, Rafaella Rocha Figueiredo, Carmélia Bomfim Jacó Rocha, Ligia Sousa, Sebastião Marcos Ribeiro Carvalho, Juliana Bassalobre Carvalho Borges

Last modified: 2014-04-03

Abstract


Introduction: Weakness of the respiratory muscles is a major cause for respiratory failure in Duchenne muscular dystrophy(DMD). Objective: To evaluate effects of inspiratory muscle training on respiratory muscle strength in patients with DMD. Method: Clinical trial with one group with five patients (DMD), aged 11.4±2.6 years, assessed by manovacuometry (MIP and MEP) and Peak Flow (PEF) in three stages: initial(baseline), five and ten session. Inspiratory muscle training, with 30% of MIP in linear load device (Threshold ®), five sets of 10 repetitions, totaling 10 sessions, three times a week. This work was approved by the ethics committee and the results were analyzed by Friedman test and Dunn test and calculation of effect size (r) of Cohen. Results: Mean initial, fifth and 10th session, respectively: MIP(cmH2O) -64, -69.8 and -86.8; MEP(cmH2O) 64, 67 and 73.6 and PEF(L/min) 210, 218 and 232. Friedmann test significant: MIP (p=0.006), MEP (p=0.003) and PEF (p=0.012). Dunn test: MIP: initial = 5sessions < 10sessions (p=0.527,p=0.040,p=0.007), a 29% improvement in initial sessions to 10th with effect size r=0.85 (major), explaining 72% of the total variance. MEP: Initial≤5sessions ≤10sessões (p=0.343,p=0.058,p=0.004), 25% improvement for initial to 10th session and effect size r=0.90 (large) explaining 81% of the total variance. PEF: Initial=5sessions<10sessions (p=0.752,p=0.027,p=0.011); improvement of 9% from initial to 10 sessions and effect size r=0.80 (major) explaining 64% of the total variance. Conclusion: Training proposed was effective in gaining respiratory strength in 10 sessions. Because the progression of DMD suggest permanent treatment aimed at maintaining and improving muscle strength.


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