ICNC2018 Abstracts & Symposia Proposals, ICNC 2014

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THE EFFECT OF DEPRESSION ON COGNITIVE PERFORMANCE IN CHILDREN WITH REFRACTORY MESIAL TEMPORAL SCLEROSIS (MTS)
Gopukumar Kumarpillai

Last modified: 2014-04-03

Abstract


Aim:

The aim of the present study focuses the difference between high and low depression and cognitive functions of Mesial Temporal Sclerosis (MTS) children, and to study the relationship between depression and cognitive performance.

Method:

Thirty-six MTS children were included in the study, and the  subjects were set up by a median split of the scores obtained on the Centre for Epidemiological Studies – Depression Scale for Children (CES-DC) high depression (N = 15) and low depression (N = 21). Standardized neuropsychological tests were employed in the domains of motor speed, mental speed, attention, working memory, executive functions and learning and memory.

Results:

Group Analysis: Mean, SD, ANOVA and correlation analyses were used to interpret the data. Individual analysis: Scores were compared with age, education and gender specific norms. Results: High and low depression groups significantly differ on  visual learning & memory [(CFT-copy, (P=0.019), CFT-IR, (P=0.01), CFT-DR- (P=0.008)]; and verbal  learning & memory [(AVLT-Total (P=0.008), AVLT-IR (P=0.01), AVLT-DR (P=0.012);  LM-IR (P=0.027)}. There is a significant relationship between high depression and the  neuropsychological variables on CFT-DR ( P=0.05), LM–IR (P=0.19), LM-DR (P=0.016) and DSST (P=0.024).

Conclusion:

  • The MTS children who performed low in cognitive functions reported higher level of depression.
  • MTS children’s cognitive impairments are seen more in attention, processing speed, learning and memory functions.
  • MTS children are not affected in the areas of focused & divided attention, motor speed,  mental speed, comprehension and executive functions.
  • It was concluded that high depression is associated with Bi-temporal involvement.

Keywords


Mesial Temporal Sclerosis children, Depression, cognitive performance

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