Last modified: 2014-04-03
Abstract
OBJECTIVES: Migraine is a significant problem and childhood migraine can significantly impair a child’s quality of life. The aim of this study is to evaluate the efficacy of prophylactic treatments of our patients diagnosed as migraine by using Pediatric Migraine Disability Assessment score(PedMIDAS).
METHODS: Children with migraine aged between 6-17 years were followed-up at least 6 months and PedMIDAS questionnaire were applied at 0, 3 and 6th months.
RESULTS: The changes between PedMIDAS scores of 0-3 month, 0-6 month ve 3-6 month of patients who were given prophylactic therapy were significantly higher than the patients who did not receive any therapy. The changes between PedMIDAS scores of 0-3 months were 21.11±14.68 days in topiramate group, 9.00±9.30 days in flunarizine group and 26.80±11.89 days in propranolol group. The changes between PedMIDAS scores of 0-3 months were significantly higher in topiramat and propranolol groups than flunarizine group(p<0.05). The number of days on analgesics treatment significantly decreased in the patients who had topiramate and propranolol treatments(p<0.05), whereas remained unchanged in flunarizine prophylaxis group(p>0.05).
CONCLUSİONS: PedMIDAS scoring system was observed to be useful when evaluating the efficacy of pharmacological agents used in the prophylactic therapy of pediatric migraine. Topiramat and propronalol therapies were shown to lower the PedMIDAS scores better than flurinazine therapy.
Keywords
References
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