ICNC2018 Abstracts & Symposia Proposals, ICNC 2014

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In vitro fertilization and cerebral palsy; the Pető Institute experience
Anna Kelemen, Éva Szabo, Gabriella Filiczki

Last modified: 2014-04-03

Abstract


Background: In vitro fertilization (IVF) may increase the risk of future cerebral palsy (CP).

Apart from prematurity, the most common risk factors include protracted or precipitate labor, placental abnormalities, infections, lasting mechanical ventilation and multiple pregnancies.

Methods: We examined children born from IVS, their handicap, the type of cerebral palsy and compared with children from control population of same age, from the same district. We analyzed both groups according to the factors which co-vary with CP such as multiple births, preterm births, neonatal complications and  parents age.

Results: The incidence of IVS amongst children with CP was doubled compared with the control kindergarten. All children were born from twin pregnancies. More than 2 embryos were transferred in 64% of cases.

In our group, CP was most likely a consequence of an increased risk of neonatal morbidity associated with multiple pregnancies.

Conclusion: Our case-series favors a more widespread use of single embryo transfer.


Keywords


cerebral palsy, in vitro fertilization, twin pregnancies, prematurity

References


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