Last modified: 2014-04-03
Abstract
BACKGROUND: Susceptibility-weighted imaging (SWI) is a three-dimensional gradient-echo magnetic resonance imaging technique with phase post-processing that accentuates the paramagnetic properties. The use of susceptibility-weighted imaging in the acute-stage of convulsive disorders in a child has not been well documented.
PATIENTS: We enrolled 11 children (5 boys and 6 girls; age range, 0-7 years; average age, 3.7 years) with convulsive disorders undertaken SWI within 2 hours after seizure termination between June 2012 and March 2014, and 10 control children (7 boys and 3 girls; age range, 0-15 years; average age, 6.4 years) with various conditions undertaken SWI other than acute-stage of convulsive disorders during the same period.
RESULTS: Conventional cranial T1- and T2-weighted images and diffusion-weighted images showed no abnormalities in all patients.5 patients with acute-stage SWI group showed transient prominence of the focal cerebral venous vasculature on SWI consistent with electroencephalographic findings, and the rest of 6 patients with this group showed prominence of the generalized cerebral venous vasculature. All patients with control group showed normal SWI findings.
CONCLUSIONS: SWI could be a useful alternative method for differentiating focal seizure from generalized seizure in the acute stage of epileptic encephalopathy in children.
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References
1) Haacke EM, Xu Y, Cheng YC, et al. Susceptibility weighted imaging (SWI). Magnet Reson Med 2004;52:612-618.
2) Sehgal V, Delproposto Z, Haacke EM, et al. Clinical applications of neuroimaging with susceptibility-weighted imaging. J Magn Reson Imaging 2005;22:439-450.
3) Iwasaki H, Takeda T, Ito T, et al. The use of susceptibility-weighted imaging for epileptic focus localization in acute-stage pediatric encephalopathy: a case report. Pediatr Neurol 2014;50:171-176.
4) Rioja E, Kerr CL, McDonell WN, et al. Effects of hypercapnia, hypocapnia, and hyperoxemia on blood oxygenation level-dependent signal intensity determined by use of susceptibility-weighted magnetic resonance imaging in isoflurane-anesthetized dogs. Am J Vet Res 2010;71:24-32.
5) Wasterlain CG, Thompson KW, Suchomelova L, et al. Brain energy metabolism during experimental neonatal seizures. Neurochem Res 2010;35:2193-2198.