Objective: Infection with human cytomegalovirus (HCMV)  is the most  frequent congenital viral infection. Central nervous system involvement and damage is especially  intensive in early primary infection. Infants with cytomegalovirus  infection are especially at risk of cerebral palsy, so early rehabilitation intervention is crucial. Only  a few  diagnostic tests are available for evaluation of the psychomotor development in very young infants. The  comparison of the two commonly used diagnostic tests were performed. Material and methods: In 24 infants ( 9 premature)  with congenital cytomegalovirus infection at the age 2 to 4 months estimation of the motor performance’s level were done using Denver test and  The Test of Infant Motor Performance (TIMP).Clinical signs of HCMV infection, serological and HCMV DNA results and birth weight, mode of delivery as well as neuroimaging results were analyzed. TIMP examination was performed in two parts- in supination position and then with using 23 specific tests. Results: Comparison of the results from Denver and TIMP tests revealed high coherence (0.65,p=0.05).Factors concerning clinical  and laboratory symptoms and signs of cytomegalovirus infection and perinatal factors have no influence on Denver and TIMP tests results. Good results in Denver test guarantees also good result in TIMP tests. Conclusions: Denver test could be effective screening method before using the TIMP test. In case of bad results in Denver test, this test cannot be used as  a final diagnostic tool in therapeutic process and  the TIMP test assessment should be obligatory.