Introduction : Schizophrenia is a serious psychiatric disorder characteristically marked by withdrawal from reality , emotional imbalance and regressive behavior. It is estimated that about 0.1 to 1% of schizophrenia cases is initiated before age of 10. The Autism Spectrum Disorder (ASD) is characterized by impaired social interaction and communication, and restricted interests and repetitive behaviors . Perinatal injuries are an important risk factor for psychiatric disorders .

Patients and Methods: Case report of a teenage evaluated at four, eight and 14 years  diagnosed as mild cerebral palsy (CP) diparetic spastic associated with the ASD and schizophrenia .

Results: ASD diagnosis was performed at age of four by Autistic Traits Scale and the DSM IV - TR criterias. Intellectual Assessment in nonverbal test (Columbia Mental Maturity Scale) were within the normal range. At eight she showed first signs of schizophrenia characterized by behavioral regression, increased isolation and detachment from reality . On examination by the same examiner at age 14 shows apathy, not understand simple orders , language restricted to a few sentences without communicative intent, frankly worse than age 4, intense stereotypies. Severe deficits in adaptive behavior on Vineland . She didn’t understand any verbal or nonverbal standardized testing .

Conclusion: ASD and schizophrenia are characterized by impairments in social interaction . It is known that CP affects the developing brain and increases the risk for both conditions which significantly worsens the prognosis of patient function .