Background: Ventriculomegaly is defined as a dilatation of 10 mm or more of the fetal lateral cerebral ventricles on ultrasound at 20 weeks gestation (1,2). It can be isolated benign finding or associated with chromosomal abnormalities, congenital infections, malformations or cerebral haemorrhage. It is graded as mild (10 -12 mm), moderate (13-15 mm) and severe (> 15 mm) based on atrium width measurement.

Aim: To assess the etiology, investigations and neurological outcome of fetal ventriculomegaly cases in our centre from 2009 to 2013

Methods: 35 women with ventriculomegaly on 20 week anomaly scan were identified from fetal medicine database. Electronic and clinical records of mother & baby were reviewed to collect data on antenatal investigations, delivery details, discharge outcome and long term neurological outcome. Three cases underwent termination of pregnancy & 32 babies were born. All women had serial USS to determine if the ventriculomegaly had returned to normal, was stable or was progressive.

Results: 32 fetuses had ventriculomegaly (21 mild, 9 moderate & 2 severe). Fetal chromosomes were normal in 9 cases. TORCH screen was normal in 30 women. 13 women had fetal MRI scans.

All 16 babies in whom mild ventriculomegaly returned to normal or was stable on serial scans were neurologically normal at birth and did not have developmental abnormality. All 5 babies with mild but progressive ventriculomegaly were neurologically normal at birth but one of these baby required insertion of VP shunt. 4 out of 11 Babies with moderate or severe ventriculomegaly had delayed development.

Conclusion: Fetuses with non-progressive isolated ventriculomegaly have good prognosis but those with moderate or severe ventriculomegaly are at risk of neurodisability.