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SUMMARY : Subacute sclerosing panencephalitis (PES) is a progressive inflammatory disease of the central nervous system related persistent infection and abnormal measles virus (Paramyxovirus), presenting high mortality and poor prognosis1. It affects primarily children and young adults, in 50 % of cases, infection history Paramyxovirus below 2 years of age2; being age a risk factor for ESP, due to immaturity of the imunne system3. The incidence is 1-4:100.000 cases1,7. The disease progresses slowly with progressively divided in 4 stages2.
OBJECTIVE : Present a case diagnosed with Subacute Sclerosing Subacute and compare the data collected with the current scientific literature.
CASE REPORT : Patient, 16 years old female with history of social isolation and difficulty in school since October 2011; evolved with changing behavior, frequent falls, myoclonus, difficulty speaking and perform their daily activities. Reported Measles box with 1 year of age without complications. Neurological examination presents poor contact lack of understanding; Walking with broad-based, with momentary stoppages due to periodic myoclonus associated with facial expression. The EEG showed characteristic for this disease stroke, as well as antibodies and hypergammaglobulinemia in the CSF.
CONCLUSION : The diagnosis is made by the previous history of Measles virus infection, presence of complexes Radermacker and anti-measles antibodies in the blood and cerebrospinal fluid; histopathological findings in brain biopsy or autópsia5. It is a disease with fatal course, and no treatment.

measles; panencephalitis; myoclonus