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Introduction: In recent years there has been much attention toelucidating existence of an association between DM1 and epilepsies in children.Previous reports identify higher prevalence in DM1 , others similar to the generalpopulation,  postulating  an association between elevated levels ofanti- glutamic acid decarboxylase (anti- GAD) antibodies in patients with DM1and epilepsy . Objective: clinical characterization patients with DM1 and seizures notassociated with hypoglycemia, and search partnership with anti GAD antibodies. Material -Method: Retrospective descriptive study, analysis of clinicalrecords. Results: 8 patients, 7 women- 1 men (fig.1), mean age start DM1 6.1 years, andpresentation first seizure 7.6 years (table 1). 7cases the diagnosis of DM1 precedes onset of seizures , 4 with partial seizures, 4 with generalized seizures,  5 have alteredEEG, 5 treatment with valproic acid, 7 have normal neuroimaging (table 2). TheGAD antibody levels measured in 7 patients were positive in 6 (table 3). Discussion: identify seizures in patients with DM1 is complicated by thepossible association with hypoglycemia. We agree with previous reports, which in most cases DM1 precedes seizure.We found no difference in number of patients with focal and generalizedseizures. Most have positivity for anti GAD antibodies, which would support theexistence of suspected autoimmune basis of the disorder. Conclusions:In this series shows arelationship between patients with DM1 and no hypoglycemic seizures, may beinvolved an autoimmune component, what would be the common factor in both disorders.

Type 1 Diabetes; Epilepsy; anti- glutamic acid decarboxylase antibodies; anti GAD antibodies