ICNC2018 Abstracts & Symposia Proposals, ICNC 2014

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ELECTROENCEPHALOGRAPHIC CHARACTERIZATION OF PATIENTS WITH PERVASIVE DISORDER DEVELOPMENT
Claudia Lopez, Maria Orellana, Alejandra Mendez, Ledia Troncoso

Last modified: 2014-04-03

Abstract


Introduction: The coexistence of epilepsy in patients with autism spectrum disorder (ASD) is a 30% and an electroencephalographic alteration reaches up to 90% according to series described. The implication that these alterations occur in language development, intellectual coefficient and the final prognosis is a matter of discussion.

Objective: To describe the electroencephalographic characteristics of patients with ASD monitored in the child neurology service.

Materials and Methods: A cohort study. Descriptive analysis of 59 patients admitted record to polyclinic pervasive developmental disorder, divided into 3 groups (Classic autistic disorder, Pervasive nonspecific and Asperger syndrome).

Results: n = 59 (boys n=52). Mean age 8.3 years (range 3-15). Clinical epilepsy in 3 patients. 41% abnormal EEG. Classic autistic patients 9/21 had abnormal EEG (generalized n=2, focal n=3, slow n=2, pharmacological n=2), 2/9 have epilepsy. In the pervasive nonspecific group, 13/31 had abnormal EEG (generalized n=1, focal n=9, slow n=2, pharmacological n=1), 7 anticonvulsant treatment them all with focal EEG. In all treated patients showed abnormal development of language. In Asperger syndrome group 5/7 with normal EEG, 2/7 with generalized abnormal EEG without current treatment.

Conclusion: Our series is similar to that described in the literature, with 41% of EEG abnormality. The decision of use antiepileptic drugs was based on the location of the electric bulb (frontal and/ or temporal) and its implication from theory in language development. However we cannot conclude if their response was only by drug treatment or as part of their evolution.


Keywords


epilepsy, autism spectrum disorder , antiepileptic drugs

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