Last modified: 2018-09-09
Abstract
Introduction: Diabetes is a chronic disease in which the pancreas either does not produce enough insulin or the cells in the body do not respond adequately, resulting in high blood glucose values. There are two main types of pediatric diabetes: type 1 diabetes mellitus (T1DM) and type 2 DM (T2DM). T1DM is the most prevalent form diagnosed in children. T1DM type is associated with a significant increased risk for epilepsy according to a recent meta-analysis and also electroencephalogram (EEG) parameters may change significantly under hypoglycemia condition in T1DM. In this study, we aim to evaluate EEGs of children with T1DM and investigate whether there is an impact of autoantibodies on EEG or not.
Methods: We reviewed EEGs of children with new onset T1DM
Results: The study group consisted of 43 children with T1DM, 25 of them (58%) were girls. Twenty-one patients had wake and sleep, 13 patients had awake and 9 patients had sleep EEG. No background abnormality was detected on EEGs; only one EEG showed spikes. No patients have experienced seizure.
Conclusions: In our study, no patients have experienced seizure in short-term follow-up and one EEG showed epileptiform discharges. Long-term follow-up studies are needed.