Last modified: 2018-09-09
Abstract
Background : Progressive weakness remains the most important symptomatology for diagnosis of Guillain Barre syndrome (GBS) . However , the perception of weakness is at times overshadowed by other symptoms as perceived by parents and health care workers, especially in the early stages in children. This was a retrospective analysis of factors prompting consideration of alternative diagnosis in children with GBS at a tertiary teaching hospital .
Methods : All children with GBS admitted from May 2013 to May 2018 were analysed. Factors prompting consideration of alternative diagnosis ( both pre and post hospitalization ) were noted.
Results : Of the forty children analysed, factors found were trivial fall in 3 children, weakness being attributed to preceding illness in 2 , severe pain in 2 , meningismus in three and presence of deep tendon reflexes in two children. One child with history of trivial fall presented to the orthopedic department . The other two had a lag period of 2 and 3 days before presenting to the hospital. Of the two children with immediate preceding illness one had a wheeze requiring nebulizations and worsening respiratory parameters were attributed to the respiratory cause. In one child , the presenting symptom was pain, weakness was found on examination.
Conclusion : Increasing awareness of these factors helps in preventing diagnostic confusions in children with GBS.