Last modified: 2018-09-09
Abstract
Introduction:
Primary headache is a common though under-diagnosed entity in childhood. Pathophysiology of this entity remains enigmatic as of today.Neurocognitive aspects may have a strong role to play in the occurrence and therapeutic response of childhood headache. There is a limited body of evidence pertaining to the neurocogntive profile of children with primary headache (1).P 300 is a neurophysiological test to assess cognition. Our current study formulated in this backdrop.
Objectives:
To find the difference in P 300 scores between children with primary headache and their age and sex matched healthy controls(Primary )
To study the neurobehavioural profile of children with primary headache with the help of IQ and VSMS scores (Secondary )
Methods:
Study design: Case-control,observational Settings: Tertiary-care hospital
Duration: 01 year ; Sample-size : 60 (30+30)
Inclusion-criteria:
Cases : Children (6-12 yrs) with primary headache brought to above hospital.
Controls:Healthy age,sex-matched children .
Exclusion-criteria: Intellectual disability,autism spectrum disorder.
Institutional ethical clearance taken. Parental consent obtained.
P300 recorded using scalp electrodes and auditory stimuli.
IQ and VSMS scoring done .
Data recorded. Appropriate statistical analysis at conclusion using SPSS 20 (IBM Corp)
Results:
(Preliminary)
Screened: 18; Included: 10(Cases).Additional 10 (controls ).
No difference in mean P300 scores between cases and controls.
Expected: significant difference in P300 scores between cases and controls.
Conclusion:
Cognitive processing and neurobehavioural profile are key grey-areas in primary headache that need to be evaluated.
Learning points:
1. Role of P300 in childhood primary headache.
2. Neurobehavioural profile in childhood primary headache.
Ref
Dick BD,RiddellRP. Cognitive and school functioning in children and adolescents with chronic pain: A critical review. Pain Res Manag 2010; 15(4): 238–244.