Neurological presentations and case illustrations of cerebral OA

ICNC2024
Symposia: The ‘Cerebral’ In Organic Acidurias: From Basics To Treatment

Neurological presentations and case illustrations of cerebral OA
Juan Darío Ortigoza-Escobar

OAD’s are a distinct subset of neurometabolic disorders that are often missed clinically as well as in the academic programs. This section will discuss the neurological presentation of cerebral OA, ranging from the milder phenotype to acute metabolic crisis, late-onset phenotypes, highlighting the associated movement disorder and other neurological (seizures, ID, psychiatric symptoms, etc.) and non-neurological symptoms. Pediatric neurologists and researchers will familiarize themselves of the state of the art in terms of therapeutic interventions in these disorders, which may be partially or totally preventable. Several of them present as common childhood neurological and neurodevelopmental problems such as developmental delay, movement disorders, cerebral palsy and epilepsy, and hence are likely to present to paediatricians. Many of these disorders include later age of onset in presentation, thus of significance to the audience of adult neurologists.Hence, this symposium will provide a timely update for this purpose.