====== Differentiating between Ohtahara syndrome and Early Myoclonic Encephalopathy ======

^ Classic differentiation between Ohtahara syndrome and early myoclonic epilepsy                                                                                                                                                                                          ^||
| Differentiation between [[content:ohtahara_syndrome]] and early myoclonic epilepsy                                                                                                                                                                                                  |||
|                                                                                 | Ohtahara Syndrome                                                       | Early Myoclonic Encephalopathy                                                                                |
| EEG pattern                                                                     | Continuous suppression burst                                            | Discontinuous pattern, suppression burst not always evident at first, and often more distinct during sleep    |
| Primary seizure type                                                            | Tonic spasms                                                            | Myoclonus                                                                                                     |
| Other seizure types                                                             | Focal motor seizures Hemiconvulsions Generalized tonic-clonic seizures    | Focal motor seizuresTonic spasms                                                                              |
| Major etiology                                                                  | Structural lesions                                                      | Metabolic abnormalities                                                                                       |
| Evolution of disease                                                            | 75% progress to West syndrome, 12% progress to [[content:lennox-gastaut_syndrome]]  | Up to 50% develop transient atypical hypsarrhythmia, with subsequent return to the suppression burst pattern  |

Adapted from: {{pubmed>long:23044011}}