Newsletters of the International Child Neurology Association
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International Conference on Juvenile Myoclonic Epilepsy
26-28 October 2012
Bel Air Hotel, The Hague, The Netherlands
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Dr GatsonIn a study presented at Experimental Biology 2012 in San Diego CA, Dr Joshua Gatson and his team from the University of Texas, Southwestern Medical Center, Dallas demonstrates for the first time the anti-inflammatory and antioxidant capabilities of estrone after traumatic brain injury. The study, conducted in male rats, compared 0.5 mg of estrone to a placebo, both given 30 minutes after the injury. It demonstrated that estrone is involved in promoting brain-derived neurotrophic factor (BDNF), which promotes cell survival. Oestrone was administered withing 30 minutes of brain injury and resulted in an increase in BDNF, suggesting that the drug given shortly after injury, could potentially increase repair mechanism.
Brain-derived neurotrophic factor mediates the neuro-protective effects of estrone after brain injury. J.W. Gatson, J. Simpkins, J. Wigginton, M-M. Liu, S. Wolf and J. Minei. Univ. of Texas Southwestern Med. Ctr. and Univ. of North Texas Hlth. Sci. Ctr. http://experimentalbiology.org
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A special interest group meeting will be held at the ICNC2012
Date: May 31, 2012
Time: 1300-1330 hrs
Venue: Mezzanine M room 7/8, Brisbane Convention Centre
Topic: Does Vigabatrin treatment in infancy bring visual field defects
Please contactThis email address is being protected from spambots. You need JavaScript enabled to view it. if you would wish to participate or contribute to this meeting.
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- Raili Sylvia Riikonen
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