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Professor Helen Cross is The Prince of Wales’s Chair of Childhood Epilepsy and Honorary Consultant in Paediatric Neurology at UCL-Institute of Child Health, Great Ormond Street Hospital for Children NHS Trust, London and Young Epilepsy, Lingfield.
Professor Cross has published widely on seizure, neuropsychological and behavioural outcomes in children who have undergone surgical resection for treatment of their epilepsy.
Her research has focused on improving outcomes for children with early onset epilepsy. Her early research was into improving imaging techniques to determine areas of likely seizure onset in children with drug resistant focal epilepsy and has developed an epilepsy surgery programme based on her research.
She conducted the first randomized controlled trial of the ketogenic diet in the treatment of children with drug resistant focal epilepsy and are endeavouring to conduct the same in the very young and adults. Recognising there was little in the way of control data with regard to neurodevelopmental progress, she initiated the North London Epilepsy in Infancy study, where a cohort of children was recruited at diagnosis in the first two years of life, and has been followed to at least three years. She is now aiming to conduct a similar study over a wider geographical area, also examining phenotypes and genotypes.
She is also endeavouring to examine mechanisms of cognitive impairment – in particular examining the relationship of sleep to memory consolidation.