Movement Disorders associated with Inborn Errors of Metabolism

ICNC2024
Symposia: Neurometabolic Disorders: Current Status and Challenges For Low Middle Income Countries

Movement Disorders associated with Inborn Errors of Metabolism
Lee-Chin Wong

Neurometabolic diseases are an important and heterogeneous group of diseases.There is also diagnostic challenge for different neurometabolic diseases. The clinical manifestations of neurometabolic diseases may be varied. In addition to the neurological presentations related to the underlying neurometabolic disease, there are other different clinical manifestations, including movement disorders. There are also different types of movement disorders in neurometabolic diseases, including chorea or dyskinesia. The movement disorders in children with neurometabolic diseases may arise from the involvement of basal ganglion or caudate nuclei, such as mitochondrial diseases or other metabolic diseases. They may also arise from the impairment of neurotransmitter synthesis, such as neurotransmitter diseases.Recognizing the specific movement disorders may also lead to correct diagnosis in the patients, especially for neurotransmitter disease. In my talk, I will summarize the clinical presentations of different movement disorders, and discuss about the diagnostic algorithm related to neurometabolic diseases and movement disorders.The treatment for specific neurometabolic diseases and movement disorders will also be discussed. We hope that after the symposium the audience, including general neurologists, may understand the diagnosis and treatment of movement disorders in children with neurometabolic diseases.

Other Lectures related to this symposium
Managing the neurodisability in neurometabolic disorders under the International Classification of Functioning (ICF), Disability and Health
The burden of inherited metabolic disorders in Bangladesh and current research priorities
Neurobehavioural and Autism Spectrum Disorders associated with Inborn Errors of Metabolism - current concepts