Journal Watch

karenskjeiKaren L. Skjei, M.D.
Assistant Professor,
Department of Neurology Co-Director,
Epilepsy Surgery Program Director,
Epilepsy Monitoring Unit,
Norton Children's Hospital

Dr. Karen Skjei is an assistant professor of Neurology and Pediatrics at the University of Louisville. She completed her undergraduate studies at Duke University, and her medical education at the University of California at San Francisco School of Medicine. She completed a residency in Pediatrics and a fellowship in Child and Adolescent Neurology at the Mayo Clinic in Rochester, New York. She completed a fellowship in Neurophysiology and Epilepsy at the Children’s Hospital of Philadelphia. Dr Skjei is currently Editor of the ICNApedia Journal Watch

87 results - showing 41 - 50
1 2 3 4 5 6 7 8 9
Ordering
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated May 10, 2016 9047 0
Cochrane Database of Systematic Reviews
The Cochrane Infectious Diseases Group (CIDG) have published an updated review to evaluate the effects of corticosteroids being used alongside anti-tuberculosis medication to treat people suffering from tuberculous meningitis.
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated February 02, 2016 9059 0
Ann Intern Med. Published online 2 February 2016
Zika virus, a mosquito-borne flavivirus that causes febrile illness associated with rash, has been rapidly emerging in the Western Hemisphere over the past few months. The virus was rarely identified until outbreaks occurred on Yap Island in the Federated States of Micronesia in 2007, French Polynesia in 2013, and Easter Island in 2014. It was initially detected in Brazil in 2015, in the northeast, and was subsequently identified in other states and several South American countries, including Colombia, Ecuador, Suriname, Venezuela, French Guyana, and Paraguay (1). Local transmission has been documented in Central America (Panama, El Salvador, Honduras, and...
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated January 07, 2016 11217 0
Lancet Neurol. 2015 Dec 23
Epidiolex® (cannabidiol or CBD) data from the physician-led expanded access program in treatment-resistant epilepsy were published in The Lancet Neurology.
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated December 19, 2015 10345 0
The Cochrane Database of Systematic Reviews 11 CD004552 (Nov 2015)
BACKGROUND Cerebral palsy is a disorder of movement and posture arising from a non-progressive lesion in the developing brain. Spasticity, a disorder of increased muscle tone, is the most common motor difficulty and is associated with activity limitation to varying degrees in mobility and self care.Oral baclofen, a gamma-aminobutyric acid (GABA) agonist, has been used in oral form to treat spasticity for some time, but it has a variable effect on spasticity and the dose is limited by the unwanted effect of excessive sedation. Intrathecal baclofen produces higher local concentrations in cerebrospinal fluid at a fraction of the equivalent...
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated December 18, 2015 10235 0
JAMA Psychiatry
The trajectory of cortical gray matter development in childhood is characterized by increase in volume resulting from early neurogenesis, peaking at puberty and subsequently losing volume and thinning by selective elimination and myelination. Although this inverted U-shaped trajectory, as well as cortical thickness has been associated with cognitive and emotional function there is no current data to relate this to childhood depression unlike in adult patients where decreased cortical gray matter has been shown to be associated with depression.
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated December 14, 2015 10014 0
PLoS Computational Biology Dec 10, 2015
Temporal lobe epilepsy (TLE) is a prevalent neurological disorder resulting in disruptive seizures. In the case of drug resistant epilepsy resective surgery is often considered. This is a procedure hampered by unpredictable success rates, with many patients continuing to have seizures even after surgery.
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated December 14, 2015 10612 0
Headache: The Journal of Head and Face Pain
Migraines can be triggered by a variety of factors, including stress, sleep disruption, noise, odors, and diet. The recent discovery that the TRPA1 ion channel transduces oxidative stress and triggers neurogenic inflammation suggests that oxidative stress may be the common denominator underlying migraine triggers. The findings of a new Headache review indicate that many of these factors converge on a common pathway involving oxidative stress.
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated November 11, 2015 10482 0
Acad Emerg Med. 2015 Nov;22(11)
In a study published online in the journal Academic Emergency Medicine, researchers from the Departments of Emergency Medicine at Orlando Regional Medical, Arnold Palmer Hospital for Children ,Orlando, The Children’s Hospital of Philadelphia and the Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania , Philadelphia examined the performance of serum glial fibrillary acidic protein (GFAP) in detecting traumatic intracranial lesions on computed tomography (CT) scan in children and youth with mild and moderate traumatic brain injury (TBI) and assessed its performance in trauma control patients without head trauma.
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated November 11, 2015 8264 1
Ann Neurol. 2015 Oct 27
In a study published online in Annals of Neurology, researchers from the University of South Australia in Adelaide have identified mutations in GATOR1 complex as the most significant cause of familial focal epilepsy identified to date.
 
0.0
 
0.0 (0)
ICNA
ICNA
Updated October 19, 2015 10070 0
Seizure. doi:10.1016/j.seizure.2015.09.007
A retrospective study on 71 children with refractory epilepsy looking at the effect of concomitant AED use on the efficacy of the ketogenic diet (KD), has suggested that Lamotrigine used alongside significantly reduced the efficacy of the diet (van der LouW et al., 2015). The study was performed by van der LouW and colleagues at Erasmus University Hospital Sophia Children's Hospital, Rotterdam and published in the journal Seizure on 21 September 2015. The study included children aged 0-18 yrs. who were started on KD between 2008-2014 and were on the diet for at least 3 months...
87 results - showing 41 - 50
1 2 3 4 5 6 7 8 9

pleasedonate